Why is a mixture classified as “Skin Corr. 1” (Corrosivity to the skin, category 1) despite the fact that no individual component shares this classification? An analogous question can be asked for “Eye Dam. 1” (Serious eye damage, category 1). The CLP Regulation It can be helpful to take a look at the CLP
How is the "acute toxicity" classification determined? The reason for this blog entry was a question from a user of the SDBcheck® online tool on the topic of acute toxicity: "How does the classification Acute Tox. 2 with H330 result, even though none of the individual components is also classified as "Acute Tox."? A
Many factors play an important role in the CLP classification "acute toxicity". Acute toxicity is predominantly based on LD50 values from animal experiments and the route of exposure. LD50 is the lethal dose for 50% of laboratory animals under specified experimental conditions. In contrast to specific target organ toxicity where the routes of exposure are
